Peripheral Expression of MACROD2 Gene Is Reduced Among a Sample of Turkish Children with Autism Spectrum Disorder

Alnak A., Ozucer I. K., ÇAĞLAYAN A. O., COŞKUN M.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.31, sa.3, ss.261-269, 2021 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/pcp.2021.21144
  • Dergi Adı: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.261-269
  • Anahtar Kelimeler: Autism, expression, family, genetics, macro domain, MACROD2, ABERRANT BEHAVIOR CHECKLIST, COPY NUMBER VARIATION, GENOME-WIDE SCAN, RATING-SCALE, ASSOCIATION, RISK, DISCOVERY, PROTEINS, VARIANT, BRAIN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Genomic variations in mono-ADP ribosylhydrolase 2 (MACROD2) have been associated with autism spectrum disorder (ASD) in recent genome-wide studies and case reports. In this study, we aimed to evaluate the MACROD2 expression profile in patients with ASD.