Relation of asymmetric dimethylarginine and cardiac involvement in systemic sclerosis

Dag S., Budulgan M., DİLEK B., Batmaz I., Ariturk Z., Nas K., ...Daha Fazla

ACTA REUMATOLOGICA PORTUGUESA, cilt.39, sa.3, ss.228-235, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 2014
  • Dergi Adı: ACTA REUMATOLOGICA PORTUGUESA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.228-235
  • Anahtar Kelimeler: Systemic sclerosis, Pulmonary hypertension, Asymmetric dimethylarginine, SCLERODERMA, DISEASE, HEART
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives: The heart is a commonly involved organ in systemic sclerosis (SSc) and pulmonary hypertension is a commonly observed complication that is associated with poor prognosis in this disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases. In this study, we aimed to contribute to an early diagnosis of cardiac involvement by evaluating ADMA and tissue Doppler echocardiographic findings in patients with SSc.