Serum osteoprotegerin is associated with carotid intima media thickness in women with previous gestational diabetes


AKINCI B., Demir T., ÇELTİK A., BARIŞ M. M., Yener S., ÖZCAN M. A., ...More

DIABETES RESEARCH AND CLINICAL PRACTICE, vol.82, no.2, pp.172-178, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.1016/j.diabres.2008.07.014
  • Journal Name: DIABETES RESEARCH AND CLINICAL PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.172-178
  • Keywords: Gestational diabetes, Osteoprotegerin, Endothelial dysfunction, Carotid intima thickness, PAI-1, SINGLE NUCLEOTIDE POLYMORPHISM, CORONARY-HEART-DISEASE, INSULIN-RESISTANCE, MYOCARDIAL-INFARCTION, SUBCLINICAL ATHEROSCLEROSIS, FIBRINOLYTIC DYSFUNCTION, ENDOTHELIAL DYSFUNCTION, PLASMA OSTEOPROTEGERIN, PROMOTER REGION, BONE-DENSITY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Circulating levels of osteoprotegerin (OPG) have been shown to be increased in patients with cardiovascular disorders and diabetes. The aim of this study was to determine serum OPG levels in women with previous gestational diabetes (GDM), and to investigate the relationship between OPG and carotid intima media thickness (IMT) and circulating cardiovascular risk factors.