Cortical sulci and bipolar disorder

Coyle T. R., Kochunov P., Patel R. D., Nery F. G., Lancaster J. L., Mangin J., ...Daha Fazla

NEUROREPORT, cilt.17, sa.16, ss.1739-1742, 2006 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 16
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1097/01.wnr.0000239957.53072.f0
  • Dergi Adı: NEUROREPORT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1739-1742
  • Anahtar Kelimeler: bipolar disorder, brain, cortical sulci, diagnostic imaging, magnetic resonance imaging, sulcal width
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

The width of cortical sulci in bipolar patients (n = 19) and healthy controls (n = 35) was examined using a novel automated technique involving magnetic resonance imaging. All sulci were wider for bipolar patients than for healthy controls. Bipolar-control differences were largest for the superior and intermediate frontal sulci, smallest for the occipital and cingulate sulci, and intermediate in magnitude for the other sulci (intraparietal, inferior frontal, and central sulci). The results were interpreted in terms of neurodegenerative-illness-related processes, which could produce cortical atrophy and result in wider sulci.