Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens

Senni, Michele; McMurray, John; Wachter, Rolf; McIntyre, Hugh; Reyes, Antonio; Majercak, Ivan; Andreka, Peter; Shehova-Yankova, Nina; Anand, Inder; YILMAZ, MEHMET; Gogia, Harinder; Martinez-Selles, Manuel; Fischer, Steffen; Zilahi, Zsolt; Cosmi, Franco; Gelev, Valeri; Galve, Enrique; Gomez-Doblas, Juanjo; Nociar, Jan; Radomska, Maria; Sokolova, Beata; Volterrani, Maurizio; Sarkar, Arnab; Reimund, Bernard; Chen, Fabian; Charney, Alan

doi:10.1002/ejhf.548

Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens

Senni M., McMurray J. J. V., Wachter R., McIntyre H. F., Reyes A., Majercak I., ...Daha Fazla

EUROPEAN JOURNAL OF HEART FAILURE, cilt.18, sa.9, ss.1193-1202, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 9
Basım Tarihi: 2016
Doi Numarası: 10.1002/ejhf.548
Dergi Adı: EUROPEAN JOURNAL OF HEART FAILURE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1193-1202
Anahtar Kelimeler: LCZ696, Sacubitril, Valsartan, ARNI, Heart failure, Tolerability
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

AimsTo assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction 35%).