Effects of terlipressin in a rat model of severe uncontrolled hemorrhage via liver injury.

BAYRAM B., HOCAOĞLU AKSAY N., ATİLLA R., KALKAN Ş.

The American journal of emergency medicine, cilt.30, sa.7, ss.1176-82, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 7
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ajem.2011.09.007
  • Dergi Adı: The American journal of emergency medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1176-82
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Animal experiments and clinical studies have shown that vasopressin infusion in cases of uncontrolled hemorrhagic shock is a promising treatment. However, there are only a few studies regarding the application of terlipressin in hemorrhagic cases. This study was designed to evaluate the effects of terlipressin vs controlled fluid resuscitation on hemodynamic variables and abdominal bleeding in a rat model of uncontrolled hemorrhage via liver injury.