Effects of terlipressin in a rat model of severe uncontrolled hemorrhage via liver injury.


BAYRAM B., HOCAOĞLU AKSAY N., ATİLLA R., KALKAN Ş.

The American journal of emergency medicine, vol.30, no.7, pp.1176-82, 2012 (SCI-Expanded) identifier identifier identifier

Abstract

Background: Animal experiments and clinical studies have shown that vasopressin infusion in cases of uncontrolled hemorrhagic shock is a promising treatment. However, there are only a few studies regarding the application of terlipressin in hemorrhagic cases. This study was designed to evaluate the effects of terlipressin vs controlled fluid resuscitation on hemodynamic variables and abdominal bleeding in a rat model of uncontrolled hemorrhage via liver injury.