Effects of epigallocatechin-3-gaRate (EGCG) on a scleroderma model of fibrosis


Kocak A., Harmanci D., Birlik M., SARIOĞLU S., YILMAZ O., ÇAVDAR Z., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.43, no.4, pp.464-473, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1515/tjb-2017-0185
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.464-473
  • Keywords: BLM induced Scleroderma, EGCG, Fibrosis, TGF-beta, MMPs, BLEOMYCIN-INDUCED SCLERODERMA, REAL-TIME PCR, SYSTEMIC-SCLEROSIS, ANIMAL-MODEL, GREEN TEA, GROWTH-FACTOR, COLLAGEN PRODUCTION, SKIN FIBROBLASTS, HEPATIC-FIBROSIS, GENE-EXPRESSION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: The aim of the present study was to evaluate the potential protective effects of epigallocatechin-3-gallate (EGCG) on fibrosis in bleomycin induced scleroderma model.