Akademik Veri Yönetim Sistemi
Turkiye Klinikleri Dermatoloji, cilt.20, sa.2, ss.106-108, 2010 (Scopus)
Hypomelanosis of Ito (HI) is a neurocutaneous disorder characterized by hypopigmented whorls, streaks and patches with irregular border along the lines of Blaschko. Although central nervous, musculoskeletal and ocular system defects are most frequent complications of HI, renal involvement has been reported less frequently. Five case reports of HI associated with renal diseases including glomerular basement membrane abnormalities, glomerulonephritis, polycystic kidney disease, glomerulocystic kidney disease or focal segmental glomerulosclerosis (FSGS) were defined in the literature. We reported a 4-year-old girl with cutaneous findings of HI who developed proteinuria in the follow-up period consistent with FSGS. Our case is presented to emphasize the necessity of following HI patients more carefully in terms of other organ defects which may develop rarely. Copyright © 2010 by Türkiye Klinikleri.