Clinical significance of basal core promoter and precore mutations in chronic hepatitis B

Ozgenc O., Ozacar T., Erensoy S., Inan N., Ari A., Kuruuzum Z., ...Daha Fazla

HEPATO-GASTROENTEROLOGY, cilt.54, sa.80, ss.2319-2323, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 80
  • Basım Tarihi: 2007
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2319-2323
  • Anahtar Kelimeler: chronic hepatitis B, basal core, promoter, precore, mutants, E-ANTIGEN SEROCONVERSION, VIRAL REPLICATION, VIRUS GENOTYPES, LAMIVUDINE THERAPY, LIVER-DAMAGE, LONG-TERM, INTERFERON, MUTANTS, PREVALENCE, INFECTION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background/Aims: The mutations in the basal core promoter and precore region of hepatitis B virus genome in hepatitis B e antigen-positive and -negative chronic hepatitis B patients have been described. The reports about their prevalence and clinical significance in the Mediterranean region where D is the predominant genotype, are very limited.