Serum apelin levels and body composition changes in breast cancer patients treated with an aromatase inhibitor


Salman T., DEMİR L., Varol U., Akyol M., Oflazoglu U., Yildiz Y., ...Daha Fazla

JOURNAL OF BUON, cilt.21, sa.6, ss.1419-1424, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 6
  • Basım Tarihi: 2016
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1419-1424
  • Anahtar Kelimeler: apelin, postmenopausal breast cancer, aromatase inhibitors, CELL-PROLIFERATION, RECEPTOR, EXPRESSION, OBESITY, APJ, LIGAND, RISK, LOCALIZATION, ADIPOSITY, PROGNOSIS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: The adipose tissue plays a role in carcinogenesis with the adipokines it generates. Apelin is an anti-obesigenic adipokine, and assumes roles in both vascularization and tumor cell proliferation. The present study aimed to investigate changes in apelin levels, in postmenopausal breast cancer (BC) patients receiving aromatase inhibitors (AIs).