Neurodegeneration and Epileptic Seizure: Earlier Than We Think


ÖZ D., ASLAN T., ÖZBEK Y., ÖZTURA İ., BAKLAN B., YENER G.

Archives of Epilepsy, cilt.28, sa.4, ss.149-151, 2022 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/archepilepsy.2022.223663
  • Dergi Adı: Archives of Epilepsy
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.149-151
  • Anahtar Kelimeler: Cognition, dementia, epilepsy, neurodegeneration, neurology, seizure
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The purpose of this study is to compare demographical and cognitive features of patients who have neurodegenerative diseases with or without seizures. Methods: This descriptive retrospective study included a total of 16 348 participants, 479 with seizures and 15 869 without seizures. Independent samples t-test and chi-square tests were used to compare age, education, Mini Mental State Examination, and gender of groups. Results: There was a significant difference between patients with seizures and without seizures in age [t(3764) = 2.815, P = .005]. It is found that patients with seizures (M = 67.51, standard deviation = 9.69) were significantly younger than patients without seizures (M = 70.37, standard deviation = 9.51). Conclusion: In all neurodegenerative diseases, especially Alzheimer’s disease, at an early age and regardless of cognitive status, diagnosis of seizures at the first admission and subsequent follow-ups is of great importance in terms of the patient’s quality of life, prognosis of the disease, and treatment options.