4th International Medical Congress of Izmir Democracy University (IMCIDU) 2022, İzmir, Türkiye, 9 - 11 Aralık 2022, ss.390-392
Introduction and Aim: The septum pellucidum is the midsagittal line structure of the brain that connects
cerebral hemispheres via corpus callosum and also lymbic system. The process of joining the septum
leaves is thought to interact with the development of other midline structures. In the adult period, septum
pellucidum variations occur when the septal fusion stops at certain levels for a reason. Among these,
cavum septum pellucidum, cavum Vergae and cavum veli interpositi are the most common variations in
which a gap is seen between the septal leaves. The aims of our study are to determine the frequency of
septum pellucidum variations, which have close anatomical and developmental connections with the
corpus callosum and limbic system elements.
Materials and Methods: The fusion defect in the posterior part of the columna fornicis of the two septum
pellucidum leaves is defined as CV. Anterosuperiorly of the pineal gland, antero-inferiorly of the
spelinum corpus callosi and columna fornicis, below the hippocampus. The structure with a diameter
greater than 10 mm in the axial section including the cerebri internae was accepted as CVI.
Results: 2957 images were examined under the inclusion criteria. 1180 male (39.9%), 1777 female
(60.1%) patients. Average age of women is 52.3 and mean age of men is 48.97. Number of people with
at least one variation (CSP, CV, CVI) 573 (19.3%). At least one variation was observed in 19.3% of
female cases and 19.4% of male cases. Depression, extrapyramidal disorders, and Alzheimer's disease
were found to be the most common in patients with septum variation, respectively. In the control group,
the frequency of extrapyramidal disorders was significantly less.
Discussion and Conclusion: After the statistical completion of the results of our study in terms of
differences between age groups and genders, it will be examined whether septum variations will make a
significant difference in diseases specific to diseases. According to our preliminary findings, it is thought
that the septum pellucidum variation may be associated with extrapyramidal disorders and should be
emphasized in further studies.