Langerhans Cell Histiocytosis of the Cervical Spine in an Adult: A Case Report

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Sayhan S., Altinel D., Erguden C., KIZMAZOĞLU C., GÜRAY DURAK M., Acar U.

TURKISH NEUROSURGERY, vol.20, no.3, pp.409-412, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.5137/1019-5149.jtn.1625-08.2
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.409-412
  • Keywords: Cervical pain, Langerhans cell histiocytosis, Diagnostic, Therapy, EOSINOPHILIC GRANULOMA, MANIFESTATIONS, DIAGNOSIS, BONE
  • Dokuz Eylül University Affiliated: Yes


We present a case of a 47-year-old-woman with a complaint of cervical pain with paresthetic appearance on her left arm. She was treated with analgetics. Further radiological evaluation because of the persistent pain revealed an osteolytic destruction of the fourth cervical vertebra. The patient underwent anterior cervical corpectomy with total excision of the tumor. Stabilization of the cervical spine was performed. Histology confirmed the diagnosis of Langerhans cell histiocytosis (LCH) of the cervical spine. This case report presents the histopathological evaluation, diagnostic work-up and the treatment procedures, because of rarity of cervical spinal LCH cases in the literature.