Saccadic Eye Movements in Patients with Mild Cognitive Impairment: A Longitudinal Study

Akkoyun M., Koçoğlu K., Eraslan Boz H., KESKİNOĞLU P., Akdal G.

Journal of Motor Behavior, cilt.55, sa.4, ss.354-372, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1080/00222895.2023.2202620
  • Dergi Adı: Journal of Motor Behavior
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, IBZ Online, BIOSIS, CINAHL, Educational research abstracts (ERA), EMBASE, MEDLINE, Psycinfo, SportDiscus
  • Sayfa Sayıları: ss.354-372
  • Anahtar Kelimeler: anti-saccade, eye movements, longitudinal study, mild cognitive impairment, pro-saccade
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Saccadic eye movements are one of the sensitive and noninvasive methods to help monitor the cognitive course of mild cognitive impairment (MCI). The study aimed to evaluate both pro and anti-saccade longitudinally and the relationship between cognitive functions and eye movements in MCI subgroups and healthy controls (HCs) at a two-year follow-up. This study revealed that the anti-saccade anticipatory responses decreased in amnestic MCI (aMCI). Correct vertical pro-saccades increased in non-amnestic MCI (naMCI), while the express saccades decreased. Our study demonstrated that longer than two years of follow-up is necessary to monitor the course of MCI. Findings of the relationships between longitudinal changes of saccades and cognitive measurements demonstrated the usability of eye movements in evaluating the process of MCI.