JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.4, no.3, pp.230-236, 2020 (ESCI)
Purpose: Radiocontrast-induced nephropathy is an important clinical problem in high-risk patients. The mechanism of cytotoxic effect of radiocontrast media on kidneys is still not fully clarified. Rac1/beta-PAK pathway has been shown to play a role in other nephropathies such as diabetic nephropathy. In this study, it was aimed to determine whether Rac1/beta-PAK signalling pathway has any role in the development of contrast-induced nephropathy (CIN).