beta-catenin gene mutation in invasive ductal breast cancer

Kizildag S., Zengel B., Vardar E., Sakizli M.

JOURNAL OF BUON, cilt.13, sa.4, ss.533-536, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2008
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.533-536
  • Anahtar Kelimeler: breast cancer, beta-catenin, cyclin D1, localization, mutation, EXON 3, COLORECTAL-CANCER, CTNNB1 MUTATIONS, CELL-ADHESION, WILMS-TUMORS, CARCINOMAS, ACTIVATION, TARGET, EXPRESSION, PATHWAY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: Aberrant accumulation of beta-catenin plays an important role in a variety of human neoplasms. In this study we analyzed the somatic mutations of the beta-catenin gene and the immunohistochemical localization of beta-catenin and cyclin D1 in invasive ductal breast cancer.