The effect of chemotherapy on symptoms and nutritional status in children with cancer


ÖZALP GERÇEKER G., Yildirim B. G., ARICIOĞLU SÜLÜN A., BEKTAŞ M., Ozdemir H. H., Malbora B.

EUROPEAN JOURNAL OF ONCOLOGY NURSING, vol.61, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 61
  • Publication Date: 2022
  • Doi Number: 10.1016/j.ejon.2022.102206
  • Journal Name: EUROPEAN JOURNAL OF ONCOLOGY NURSING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, ASSIA, CINAHL, EMBASE, MEDLINE, Psycinfo
  • Keywords: Pediatric, Cancer, Nutrition, Malnutrition, Chemotherapy, Symptom, QUALITY-OF-LIFE, HOSPITALIZED CHILDREN, SCREENING TOOL, PEDIATRIC-PATIENTS, CLINICAL-OUTCOMES, MALNUTRITION, ADOLESCENTS, RISK, VALIDATION, LEUKEMIA
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: This observational study carried out to determine the incidence of poor nutritional status and symptom burden in children undergoing chemotherapy treatment. Methods: The research data collected from 187 children between the ages of 7-18 at pediatric hematology -oncology units in Izmir. The data of the study collected with Screening Tool for Risk of impaired Nutritional Status and Growth (STRONGkids), and the Memorial Symptom Assessment Scale (MSAS). Results: Patients reported a mean (SD) of 14.1 (8.1; range, 1-30) symptoms, and 43.9% were underweight. According to the STRONGkids, 62% had a high risk for malnutrition. The incidence of all symptoms increased as the Z-score of the patients worsens. There was a significant positive correlation between mean symptoms and STRONGkids malnutrition risk score, and Z-score (p < .001). Conclusion: Most of the patients were at high risk of malnutrition. It observed that chemotherapy treatment led to malnutrition. The patients with high risk for malnutrition according to the STRONGkids and severe malnutrition according to the Z-score experienced more symptoms.