Differences in Poly(ADP-ribose) Polymerase1-(PARP1-) and Proliferative Cell Nuclear Antigen (PCNA) Immunoreactivity in Patients Who Experienced Successful and Unsuccessful Microdissection Testicular Sperm Extraction Procedures

Akarsu, Suleyman; Buke, Baris; GÜRGEN, SEREN; Akdemir, Serkan; Gode, FUNDA; Bicer, Merve; Tekindal, Mustafa; Isik, Ahmet

Differences in Poly(ADP-ribose) Polymerase1-(PARP1-) and Proliferative Cell Nuclear Antigen (PCNA) Immunoreactivity in Patients Who Experienced Successful and Unsuccessful Microdissection Testicular Sperm Extraction Procedures

Atıf İçin Kopyala

Akarsu S., Buke B., GÜRGEN S. G., Akdemir S., Gode F., Bicer M., ...Daha Fazla

UROLOGY JOURNAL, cilt.14, sa.5, ss.5018-5022, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 14 Sayı: 5
Basım Tarihi: 2017
Dergi Adı: UROLOGY JOURNAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.5018-5022
Anahtar Kelimeler: Azoospermia, Micro-Tese, PCNA, PARP-1, NONOBSTRUCTIVE AZOOSPERMIA, OXIDATIVE STRESS, DNA-DAMAGE, APOPTOSIS, SPERMATOGENESIS, DEATH, FRAGMENTATION, FERTILIZATION, SPERMATOGONIA, EXPRESSION
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Purpose: The aim of this study is to evaluate expression of deoxyribonucleic acid (DNA) synthesis and repair markers in testicular tissues of azoospermic men in whom sperm retrieval could and could not be achieved as a result of microdissection testicular sperm extraction (micro-TESE) procedure.