Atıf İçin Kopyala
de Zwarte S. M. C., Brouwer R. M., Agartz I., Alda M., Aleman A., Alpert K. I., ...Daha Fazla
BIOLOGICAL PSYCHIATRY, cilt.86, sa.7, ss.545-556, 2019 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
86
Sayı:
7
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Basım Tarihi:
2019
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Doi Numarası:
10.1016/j.biopsych.2019.03.985
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Dergi Adı:
BIOLOGICAL PSYCHIATRY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.545-556
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Anahtar Kelimeler:
Bipolar disorder, Familial risk, Imaging, Meta-analysis, Neurodevelopment, Schizophrenia, GRAY-MATTER VOLUME, VOXEL-BASED MORPHOMETRY, HIGH GENETIC RISK, SOCIOECONOMIC-STATUS, SCHOOL PERFORMANCE, TWINS DISCORDANT, PREMORBID IQ, METAANALYSIS, CHILDHOOD, PREDISPOSITION
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Dokuz Eylül Üniversitesi Adresli:
Evet
Özet
BACKGROUND: Schizophrenia and bipolar disorder share genetic liability, and some structural brain abnormalities are common to both conditions. First-degree relatives of patients with schizophrenia (FDRs-SZ) show similar brain abnormalities to patients, albeit with smaller effect sizes. Imaging findings in first-degree relatives of patients with bipolar disorder (FDRs-BD) have been inconsistent in the past, but recent studies report regionally greater volumes compared with control subjects.