Significance of tissue laminin P(1) elastase and fibronectin levels in transitional cell carcinoma of the bladder.

Kirkali G., Tuzel E., Guler C., Gezer S., Kirkali Z.

European urology, cilt.39, sa.3, ss.292-9, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1159/000052456
  • Dergi Adı: European urology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.292-9
  • Anahtar Kelimeler: bladder, transitional cell carcinoma, laminin P-1, fibronectin, elastase, prognostic markers, CANCER, TUMORS, LINES, LOCALIZATION, EXPRESSION, METASTASIS, ONCOFETAL, INVASION, DISEASE, THERAPY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Elastase is a serine protease which hydrolyses connective tissue components. Laminin and fibronectin also play an important role in progression and invasion of cancer. The purpose of this study is to investigate the relation between tissue elastase, laminin P-1 and fibronectin levels and tumor characteristics, and analyze the potential of these as prognostic factors in transitional cell carcinoma (TCC) of the bladder.