Serum motilin levels and motilin gene polymorphisms in children with functional constipation


Ulusoy E., Arslan N., Küme T., Ülgenalp A., Çıralı C., Giray Bozkaya Ö., ...More

MINERVA PEDIATRICS, vol.73, no.5, pp.420-425, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.23736/s2724-5276.16.04369-x
  • Journal Name: MINERVA PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.420-425
  • Keywords: Child, Constipation, Motilin, Genetic polymorphism, GASTROINTESTINAL DISORDERS, CHILDHOOD CONSTIPATION, PANCREATIC-POLYPEPTIDE, PLASMA-LEVELS
  • Dokuz Eylül University Affiliated: Yes

Abstract

BACKGROUND: Functional constipation is an important clinical problem among chidren all over the world. Its main cause is not completely understood. Motilin is a gastrointestinal hormone that increases intestinal motility. In this study, we aimed to investigate the serum motilin levels and its relationship with stool consistency and motilin gene polymorphisms in constipated children.