Unravelling the interplay between hyperkalaemia, renin-angiotensin-aldosterone inhibitor use and clinical outcomes. Data from 9222 chronic heart failure patients of the ESC-HFA-EORP Heart Failure Long-Term Registry

Rossignol, Patrick; Lainscak, Mitja; Crespo-Leiro, Maria; Laroche, Cecile; Piepoli, Massimo; Filippatos, Gerasimos; Rosano, Giuseppe; Savarese, Gianluigi; Anker, Stefan; Seferovic, Petar; Ruschitzka, Frank; Coats, Andrew; Mebazaa, Alexandre; McDonagh, Theresa; Sahuquillo, Ana; Penco, Maria; Maggioni, Aldo; Lund, Lars

doi:10.1002/ejhf.1793

Unravelling the interplay between hyperkalaemia, renin-angiotensin-aldosterone inhibitor use and clinical outcomes. Data from 9222 chronic heart failure patients of the ESC-HFA-EORP Heart Failure Long-Term Registry

Rossignol P., Lainscak M., Crespo-Leiro M. G., Laroche C., Piepoli M. F., Filippatos G., ...Daha Fazla

EUROPEAN JOURNAL OF HEART FAILURE, cilt.22, sa.8, ss.1378-1389, 2020 (SCI-Expanded)

Yayın Türü: Makale / Kısa Makale
Cilt numarası: 22 Sayı: 8
Basım Tarihi: 2020
Doi Numarası: 10.1002/ejhf.1793
Dergi Adı: EUROPEAN JOURNAL OF HEART FAILURE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
Sayfa Sayıları: ss.1378-1389
Anahtar Kelimeler: Hyperkalaemia, Hypokalaemia, Heart failure, Renin-angiotensin-aldosterone system inhibitors, Prognosis, Mineralocorticoid receptor antagonists
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Aims We assessed the interplay between hyperkalaemia (HK) and renin-angiotensin-aldosterone system inhibitor (RAASi) use, dose and discontinuation, and their association with all-cause or cardiovascular death in patients with chronic heart failure (HF). We hypothesized that HK-associated increased death may be related to RAASi withdrawal.