Gemcitabine plus infusional 5-fluorouracil and high dose leucovorin in advanced stage pancreatic cancer


Oztop I., Alacacioglu A., ÜNEK İ. T., Tarhan O., Somali I., Cokmert S., ...Daha Fazla

JOURNAL OF BUON, cilt.15, sa.3, ss.462-469, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2010
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.462-469
  • Anahtar Kelimeler: advanced stage, 5-fluorouracil, gemcitabine, pancreatic cancer, PHASE-III TRIAL, COOPERATIVE-ONCOLOGY-GROUP, ORAL FLUOROPYRIMIDINE CARBAMATE, METASTATIC COLORECTAL-CANCER, 1ST-LINE TREATMENT, RANDOMIZED-TRIAL, ADVANCED-CARCINOMA, ITALIAN GROUP, FOLINIC ACID, FLUOROURACIL
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: Advanced pancreatic cancer (APC) has a poor prognosis and chemotherapy remains the primary treatment modality. Gemcitabine (GEM) and 5-fluorouracil (5-FU) are the most active drugs in the treatment of pancreatic cancer This study evaluated the efficacy and tolerability of the combination of these agents in APC.