UroVysion fluorescence in situ hybridization (UroVysion FISH) assay for detection of bladder cancer in voided urine of Turkish patients: a preliminary study

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DODURGA Y., BİRAY AVCI Ç., Yilmaz S., NAZLI O., ÇOĞULU M. Ö., ÇANKAYA T., ...Daha Fazla

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, cilt.17, sa.2, ss.156-160, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5114/wo.2013.34619
  • Dergi Adı: WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.156-160
  • Anahtar Kelimeler: UroVysion FISH, bladder cancer, voided urine, cytology, TRANSITIONAL-CELL CARCINOMA, UROTHELIAL CARCINOMA, CYTOLOGY, MULTITARGET, SURVEILLANCE, UTILITY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Bladder cancer is the fourth most common cancer in men and the fifth most common cancer worldwide. UroVysion FISH has high sensitivity and specificity for urothelial carcinoma detection. We investigated the genetic marker detected by the UroVysion FISH technique in diagnosis of Turkish bladder cancer patients and compared these results with the urine cytology and cystoscopy. Urine specimens were analyzed using UroVysion FISH probes for abnormalities in centromeric chromosomes 3, 7, and 17 and locus-specific 9p21.