Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: A longitudinal proton magnetic resonance spectroscopy study


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Aydin B., Yurt A., Gokmen N., Renshaw P., Olson D., Yıldız A.

JOURNAL OF AFFECTIVE DISORDERS, vol.206, pp.315-320, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 206
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jad.2016.09.002
  • Journal Name: JOURNAL OF AFFECTIVE DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.315-320
  • Keywords: N-acetylaspartate, Magnetic resonance spectroscopy, Mania, Euthymia, Dorsomedial prefrontal cortex, DORSOLATERAL PREFRONTAL CORTEX, ACETYL-ASPARTATE, MITOCHONDRIAL DYSFUNCTION, DISORDER, MANIA, SCALE, SCHIZOPHRENIA, METAANALYSIS, ILLNESS, BRAIN
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Neurochemical changes are responsible for bipolar disorder (BD) pathophysiology. Despite current progress in BD research, mood- and trait-related alterations in BD continue to elicit further investigation.