The Effects of Doxycycline on Peritoneal Fibrosis Induced by Chemical Peritonitis in Rats

Yildiz S., ÇAVDAR Z., OKTAY G., SARIOĞLU S., Guneli E., YILMAZ O., ...Daha Fazla

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, cilt.27, sa.1, ss.49-56, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5262/tndt.2017.1003.25
  • Dergi Adı: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.49-56
  • Anahtar Kelimeler: MMPs, MMP inhibition, Doxycycline, Peritoneal fibrosis, MATRIX METALLOPROTEINASES, MESOTHELIAL CELLS, INHIBITORS, INJURY, MMP-9, DIALYSIS, MODEL
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

OBJECTIVE: We investigated the effects of doxycycline on changes in peritoneal morphology, matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) activities in peritoneal lavage fluids in a rat model of peritoneal fibrosis due to chemical peritonitis.