The Effects of Doxycycline on Peritoneal Fibrosis Induced by Chemical Peritonitis in Rats


Yildiz S., ÇAVDAR Z., OKTAY G., SARIOĞLU S., Guneli E., YILMAZ O., ...More

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.27, no.1, pp.49-56, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.5262/tndt.2017.1003.25
  • Journal Name: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.49-56
  • Keywords: MMPs, MMP inhibition, Doxycycline, Peritoneal fibrosis, MATRIX METALLOPROTEINASES, MESOTHELIAL CELLS, INHIBITORS, INJURY, MMP-9, DIALYSIS, MODEL
  • Dokuz Eylül University Affiliated: Yes

Abstract

OBJECTIVE: We investigated the effects of doxycycline on changes in peritoneal morphology, matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) activities in peritoneal lavage fluids in a rat model of peritoneal fibrosis due to chemical peritonitis.