Efficacy of parthenolide on lung histopathology in a murine model of asthma


Ankan-Ayyildiz Z., Karaman M., ÖZBAL S., Bagriyamk A., Yilmaz O., Karaman O., ...More

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.45, no.1, pp.63-68, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1016/j.aller.2016.06.005
  • Journal Name: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.63-68
  • Keywords: Asthma, Lung histology, Murine model, Parthenolide, Tanacetum Parthenium, NF-KAPPA-B, ALLERGIC AIRWAY INFLAMMATION, CYSTIC-FIBROSIS CELLS, SESQUITERPENE LACTONES, EPITHELIAL-CELLS, ACTIVATION, EXPRESSION, INHIBITOR, BLOCKADE, PATHWAY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Parthenolide is the active constituent of the plant Tanacetum parthenium' (Feverfew) which has been used for centuries as a folk remedy for inflammatory conditions.