Turkish Neonatal Society guideline on the management of respiratory distress syndrome and surfactant treatment

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ÖZKAN H., ERDEVE Ö., Kutman H. G. K.

TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS, cilt.53, 2018 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/turkpediatriars.2018.01806
  • Dergi Adı: TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Anahtar Kelimeler: Antenatal steroids, caffeine, oxygenation, respiratory distress syndrome, surfactant, ventilation, BIRTH-WEIGHT INFANTS, PRETERM INFANTS, NASAL CPAP, THERAPY, METAANALYSIS, MULTICENTER, OXYGENATION, VENTILATION, PRESSURE, DELIVERY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Respiratory distress syndrome is the leading cause of respiratory failure in preterm infants. The incidence and severity of respiratory distress syndrome are inversely related to the gestational age of the newborn. The major underlying pathophysiologic mechanisms are surfactant deficiency and anatomic, structural immaturity of the lung. Recent improvements such as antenatal steroid treatment to enhance pulmonary maturity, appropriate resuscitation facilitated by placental transfusion and immediate use of continuous positive airway pressure for alveolar recruitment, early rescue administration of surfactant, ventilation with gentler modes to minimize damage to the immature lungs, and the other supportive therapies have significantly decreased respiratory distress syndrome-related morbidity and mortality. This guideline was addressed to overview the mentioned improvements in order to standardize respiratory distress syndrome management in neonatal intensive care units in Turkey.