Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC-EORP Heart Failure Long-Term Registry

Kapelios, Chris; Laroche, Cecile; Crespo-Leiro, Maria; Anker, Stefan; Coats, Andrew; Diaz-Molina, Beatria; Filippatos, Gerasimos; Lainscak, Mitja; Maggioni, Aldo; McDonagh, Theresa; Mebazaa, Alexandre; Metra, Marco; Moura, Brenda; Mullens, Wilfried; Piepoli, Massimo; Rosano, Giuseppe; Ruschitzka, Frank; Seferovic, Petar; Lund, Lars

doi:10.1002/ejhf.1796

Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC-EORP Heart Failure Long-Term Registry

Kapelios C. J., Laroche C., Crespo-Leiro M. G., Anker S. D., Coats A. J. S., Diaz-Molina B., ...Daha Fazla

EUROPEAN JOURNAL OF HEART FAILURE, cilt.22, sa.8, ss.1424-1437, 2020 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 8
Basım Tarihi: 2020
Doi Numarası: 10.1002/ejhf.1796
Dergi Adı: EUROPEAN JOURNAL OF HEART FAILURE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
Sayfa Sayıları: ss.1424-1437
Anahtar Kelimeler: Loop diuretics, Furosemide, Drug titration, Chronic heart failure, Prognosis, Mortality
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Aims Guidelines recommend down-titration of loop diuretics (LD) once euvolaemia is achieved. In outpatients with heart failure (HF), we investigated LD dose changes in daily cardiology practice, agreement with guideline recommendations, predictors of successful LD down-titration and association between dose changes and outcomes.