Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery

Battersby N., Glasbey J. C., Neary P., Negoi I., Kamarajah S., Sgro A., ...Daha Fazla

COLORECTAL DISEASE, cilt.20, ss.58-68, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/codi.14361
  • Dergi Adı: COLORECTAL DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.58-68
  • Anahtar Kelimeler: Rectal surgery, rectal cancer, pathology, radiology, neoadjuvant therapy, surgical oncology, deferral of surgery
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

IntroductionThe mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR) rate and the reliability of detecting a cCR by conventional pre-operative imaging.