Atıf İçin Kopyala
ULUSOY Ş., Ozkan G., BALABAN YÜCESAN F., ERSÖZ Ş., ÖREM A., Alkanat M., ...Daha Fazla
NEPHROLOGY, cilt.17, sa.4, ss.372-379, 2012 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
17
Sayı:
4
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Basım Tarihi:
2012
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Doi Numarası:
10.1111/j.1440-1797.2012.01565.x
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Dergi Adı:
NEPHROLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.372-379
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Anahtar Kelimeler:
apoptosis, cyclosporine, cyclosporine A-induced nephropathy, grape seed proanthocyanidin extract, nephropathy, oxidative stress, INDUCED NEPHROTOXICITY, OXIDATIVE STRESS, EXPERIMENTAL-MODEL, KIDNEY INJURY, RENAL INJURY, RATS, ACTIVATION, EXPRESSION, ACID, MICE
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Dokuz Eylül Üniversitesi Adresli:
Hayır
Özet
Aim: Although the pathogenesis of cyclosporine (CsA) nephropathy is not completely understood, it is attributed to oxidative damage and apoptosis. Grape seed proanthocyanidin extract (GSPE) is a molecule with antioxidant and anti-apoptotic properties. Our aim was to demonstrate the effects of GSPE in preventing CsA nephropathy.