In this study, the state of the five stations' quality was assessed on the basis of determination of temporal and spatial variability of nutrients with physicochemical variables. Besides this, organic matter of sediment, secchi disc depth and suspended solids were also determined. The samples were collected seasonally from different areas such as harbor and important touristic marinas along the eastern Aegean during June 2008-2009. As a result, the nutrients ranged between NH4: 0.10-25.6, NO2: 0.01-1.5, NO3: 0.19-7.0, o.PO4: 0.17-6.8, TPO4: 0.32-9.6 and Si: 030-13.8 mu M, respectively. Precipitation leads to large changes in temperature, salinity, dissolved oxygen and nutrients. The highest nutrient values in this study were observed during the rainy season except o.PO4-P and TPO4-P. However, the physico-chemical variables have exhibited considerable temporal variations while nutrients showed spatial differences. The relatively high nutrient increase in the sampling stations coupled with surface runoff events during rainy period and pollution arising from both point and non-point sources. (C) 2012 Elsevier Ltd. All rights reserved.