Phenotype properties and status of corticosteroid resistance among patients with uncontrolled asthma.

Çımrın A. H., Akpinar B., Tertemiz K. C., Omeroglu G., Alpaydin A., Ellidokuz H., ...More

Allergologia et immunopathologia, vol.41, no.5, pp.304-9, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 5
  • Publication Date: 2013
  • Doi Number: 10.1016/j.aller.2012.04.009
  • Journal Name: Allergologia et immunopathologia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.304-9
  • Keywords: Glucocorticoid lymphocyte proliferation suppression test, Glucocorticoid resistance, Severe asthma, Asthma phenotype, Uncontrolled asthma, LYMPHOCYTE-T ACTIVATION, GLUCOCORTICOID RESISTANCE, DISEASE SEVERITY, CELLS, PROLIFERATION, CYCLOSPORINE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Control cannot be achieved in some asthmatics although optimal monitoring and treatment is administered. Glucocorticoid (GC) resistance is one of the reasons of poor asthma control. We aimed to investigate GC resistance by lymphocyte proliferation suppression test (LPST) in uncontrolled asthmatics.