Overweight and Obesity in Children Under Phenylalanine Restricted Diet


Ozturk Y., Gencpinar P., Erdur B., Tokgoz Y., Isik I., Akin S. B.

HONG KONG JOURNAL OF PAEDIATRICS, cilt.23, sa.2, ss.169-172, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 2
  • Basım Tarihi: 2018
  • Dergi Adı: HONG KONG JOURNAL OF PAEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.169-172
  • Anahtar Kelimeler: Hyperphenylalaninaemia, Obesity, Overweight, Phenylalanine restricted medical diet, Phenylketonuria, PHENYLKETONURIA, PREVALENCE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: The aim of this study is to determine the obesity and overweight frequency in children with phenylketonuria (PKU) and hyperphenylalaninaemia (HPA). Methods: From the patients' demographic data, diagnosis, type of diet, weight for height, body mass index, serum phenylalanine concentrations were obtained and recorded. Results: Four hundred and forty charts were evaluated and 288 of them were enrolled in the study. Two hundred and forty-six (85.4%) were under phenylalanine-restricted diet with protein support. Of those, 23 (9.3%) were obese and 16 (6.5%) were overweight. When we compared the obesity ratio of 246 patients with PKU and HPA to the obesity ratio in the Turkish population, the difference was statistically significant (p=0.025). Conclusion: The frequency of obesity was higher in PKU and HPA children who underwent phenylalanine-restricted diet treatment than in the normal population in Turkey. Detailed studies are needed to increase the understanding of the obesity risk factors in this special disorder group.