An In-House Method for Molecular Monitoring of BCR-ABL

Sercan H. O., Ozturk I., Caliskan C., Pehlivan M., Sercan Z.

TURKISH JOURNAL OF HEMATOLOGY, cilt.29, sa.4, ss.348-353, 2012 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5505/tjh.2012.14892
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.348-353
  • Anahtar Kelimeler: Chronic myeloid leukemia, BCR-ABL, Real-time PCR, Molecular response, HARMONIZING CURRENT METHODOLOGY, RESIDUAL DISEASE DETECTION, POLYMERASE-CHAIN-REACTION, CHRONIC MYELOID-LEUKEMIA, RT-PCR, STANDARDIZATION, TRANSCRIPTS, IMATINIB, RECOMMENDATIONS, RESPONSES
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: At present, there are a limited number of facilities in Turkey that can provide reliable real-time quantitative (RQ)-PCR BCR-ABL results. The present study aimed to test a cost-effective, in-house method of BCR-ABL quantification, including verification of the method by RQ-PCR validation tests.