DELETION-6Q IN 3 CASES OF MIXED-TYPE LIPOSARCOMA IN ADDITION TO T(12-16)(Q13-P11)

ALTUNGOZ O., MELONI A., PEIER A., ZALUPSKI M., SPANIER S., BROOKS J., ...Daha Fazla

CANCER GENETICS AND CYTOGENETICS, cilt.79, sa.2, ss.104-110, 1995 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 79 Sayı: 2
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1016/0165-4608(94)00180-j
  • Dergi Adı: CANCER GENETICS AND CYTOGENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Academic Search Premier
  • Sayfa Sayıları: ss.104-110
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

We report the cytogenetic findings in three mixed liposarcoma following short-term cultures. During the course of cytogenetic investigation of various types of liposarcomas, we observed an interstitial deletion of the long arm of chromosome 6 together with the translocation (12;16) (q13;p11) in three tumors. Translocation (12;16) is associated with myxoid and mixed (myxoid/round cell) liposarcomas, although deletion of chromosome 6 has been observed in only a few of these tumors. Our findings suggest that del(6), as an additional change in myxoid liposarcoma, is probably related to tumor progression.