Evaluation of serum xenin and ghrelin levels and their relationship with nonalcoholic fatty liver disease and insulin resistance in obese adolescents

Arslan N., Sayin O., Tokgoz Y.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.37, no.11, pp.1091-1097, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1007/s40618-014-0160-z
  • Journal Name: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1091-1097
  • Keywords: Adolescents, Obesity, Ghrelin, Xenin, Fatty liver disease, IMPAIRED GLUCOSE-TOLERANCE, PEPTIDE XENIN, CHILDREN, SECRETION, HUMANS, LEPTIN, PLASMA, DEGRADATION, HOMEOSTASIS, OVERWEIGHT
  • Dokuz Eylül University Affiliated: Yes

Abstract

Aim Xenin is a peptide of the neurotensin/xenopsin/xenin family secreted from gastric cells and other tissues. The first aim of this study was to investigate the serum xenin and ghrelin levels in obese children and compare the patients with healthy controls. The second aim was to compare the xenin levels in patients with nonalcoholic fatty liver disease (NAFLD) and also with insulin resistance with the patients without these complications.