Otoprotective effect of recombinant erythropoietin in a model of newborn hypoxic-ischemic encephalopathy

OLGUN Y., KIRKIM G., KOLATAN H. E., KİRAY M., BAĞRIYANIK H. A., Serbetcioglu B., ...Daha Fazla

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.77, sa.5, ss.739-746, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.ijporl.2013.01.029
  • Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.739-746
  • Anahtar Kelimeler: Hypoxic-ischemic encephalopathy, Hearing loss, Erythropoietin, POSTNATAL ASPHYXIA, INJURY, INFANTS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study is to test the hypotheses that central auditory pathology as well as inner ear pathology is contributing mechanisms to observed hypoxic-ischemic encephalopathy (HIE) induced hearing loss and that recombinant erythropoietin (rhEPO) will reduce this cellular pathology and attenuate hearing loss.