The Comparison of the Effects of "Trometamol; Tris-Hydroxymethylaminomethane" and "Sodium Bicarbonate" Treatments on Mortality and Survival Time in Experimental Metabolic Acidosis Induced by Methanol Intoxication


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Bolatkale M., Ersoy G., Yanturali S., Yilmaz O., Can C., Acara A. C., ...More

EURASIAN JOURNAL OF EMERGENCY MEDICINE, vol.17, no.1, pp.22-27, 2018 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.5152/eajem.2018.69772
  • Journal Name: EURASIAN JOURNAL OF EMERGENCY MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.22-27
  • Keywords: Metabolic acidosis, methanol, Tris-hydroxymethylaminomethane, sodium bicarbonate, rat, THAM, AMINOMETHANE, ACIDEMIA, THERAPY, ALCOHOL, STATES, RATS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Aim: Metabolic acidosis is the most serious complication of methanol intoxication, which needs urgent treatment. The aim of this study was to investigate effects of "Trometamol; Tris-hydroxymethylaminomethane" (THAM) and "Sodium Bicarbonate" (NaHCO3) treatments on mortality and survival time in rats with metabolic acidosis induced by intragastric-administered methanol.