Genetic diversity is fundamental for adaptation and essential to species survival, hence for nature’s contributions to people. Furthermore, genetic knowledge supports the effective use of resources to ensure the holistic protection of biodiversity. While genetic diversity data and indicators are available, they are often not integrated into species management and monitoring schemes in Europe due to a lack of capacity. Furthermore, current national policies and practices have not yet ‘adapted’ to the new Global Biodiversity Framework. In order to better understand genetic diversity in species and their populations and actively use it to monitor and safeguard biodiversity, there is an urgent need to refine, assess, inform and facilitate the implementation of genetic diversity data and indicators across European countries. This implementation of genetic diversity data should be achieved by including practitioners, companies, policymakers and the wider public. The needs of all these stakeholders should be investigated and taken into account in order for collaborations to be inclusive and effective, as such, building knowledge, capacity and trust among partners. Hence, GENOA will co-create and improve the procedures, methods and data on genetic diversity (indicators) and co-develop tailored dissemination packages to reach out to and exchange with targeted stakeholders to enable a better understanding of genetic diversity information. In addition, the monitoring, reporting and application of genetic data will improve, which will contribute to the conservation of biodiversity at all levels.