ENABLE: ENdoscopic mucosa Ablation device for Barrett s esophagus using infrared Lasers


Tozburun S. (Yürütücü)

TÜBİTAK Projesi, 2016 - 2017

  • Proje Türü: TÜBİTAK Projesi
  • Başlama Tarihi: Mayıs 2016
  • Bitiş Tarihi: Mayıs 2017

Proje Özeti

The primary objective of the proposed Project is to develop a prototype Endoscopic Mucosal Ablation (EMA) device that ablate (damage) the mucosa layer of the esophagus to a depth sufficient to eliminate the lesion, but not sufficient deep to induce residual thermal effects within the deeper tissue layers. By delivering negative-pressure (a vacuum), the device basically extends the mucosa layer above and away from its underlying layers to achieve a well-confined therapeutic effect. In other words, the target tissue is pulled into the recessed region of the device through a vacuum force. A laser operating at the wavelength of 1550 nm is then activated for achieving local photothermal mucosal ablation. With confinement of therapeutic effect, it is aimed that deeper tissue structures are partially separated from ablation region.