Namık Kemal Tıp Dergisi, vol.6, no.3, pp.109-116, 2018 (Peer-Reviewed Journal)
Aim: Acute bronchiolitis is the most common lowerrespiratory tract infection of children younger than 2 years ofage. There aren't any standardized diagnostic criteria andseverity assessment classifications for acute bronchiolitisavailable in literature. Mean platelet volume (MPV) has shownto be effected in inflammatory conditions and to ourknowledge there's only one recent study in children with acutebronchiolitis that demonstrated an association between MPVchange and acute brınchiolitis.Materials and Methods: In this retrospective study weenrolled 555 children diagnosed with Acute bronchiolitis and516 healthy infants with a matching age and sex.Results: MPV levels were found significantly higher in patientgroup (8,2 ± 0,8 fL) than the control group (7,9 ± 0,8 fL). Interms of hospitalization need, no significant difference wasdetected between the MPV values of the hospitalized groupand the outpatients (8,3±0,8 fL; 8,2±0.7 fL, respectively).Conclusions: In conclusion, our data show that MPV valuesare significantly elevated in acute bronchiolitis compared tohealthy infants. However, MPV can't be used as a guidance inattack severity nor can it predict hospitalization and systemicsteroid need.