Copy For Citation
Guevendi G. F., EROĞLU H. A., MAKAV M., Guvendi B., Adalre Y.
LIFE SCIENCES, vol.262, 2020 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
262
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Publication Date:
2020
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Doi Number:
10.1016/j.lfs.2020.118558
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Journal Name:
LIFE SCIENCES
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
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Keywords:
Iron overload, Hepatotoxicity, Selenium, Ozone, Antioxidant, CADMIUM-INDUCED HEPATOTOXICITY, OXIDATIVE STRESS, INFLAMMATION, THERAPY, ANTIOXIDANT
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Dokuz Eylül University Affiliated:
No
Abstract
Aims: Iron is an important metal ion as a biocatalyst on the other hand iron overload causes various diseases. Iron overload can result in fibrosis and hepatocellular carcinoma with various pathophysiological mechanisms, including oxidative damage in the liver. Therefore; in this study the effects of ozone and selenium-whose antioxidant properties are known- were evaluated in liver injury induced by iron overload.