Expression of transforming growth factor-beta-1 and p27(Kip1) in pancreatic adenocarcinomas: relation with cell-cycle-associated proteins and clinicopathologic characteristics

Creative Commons License

Culhaci N., Sagol Ö., Karademir S., Astarcioglu H., Astarcioglu I., Soyturk M., ...Daha Fazla

BMC CANCER, cilt.5, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1186/1471-2407-5-98
  • Dergi Adı: BMC CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: The purpose of our study was to investigate the immunohistochemical expression of TGF-beta 1 and p27 in pancreatic adenocarcinomas and to compare the findings with the clinicopathological features and survival. We also aimed to evaluate the expression of TGF-beta 1 and p27 in the context of other cell cycle and proliferation markers such as cyclin D1 and Ki-67.