Dokuz Eylül Üniversitesi Hastanesinde 2003-2006 yıllarında üretilen Haemophilus influenzae Suşlarının Antibiyotik Duyarlılıkları

Creative Commons License

Özkul H., Özbek Ö. A., Çoban H., Gülay Z.

ANKEM Dergisi, cilt.21, sa.2, ss.86-90, 2007 (Hakemli Dergi)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 2
  • Basım Tarihi: 2007
  • Dergi Adı: ANKEM Dergisi
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.86-90
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet


Haemophilus influenzae is one of the most important causes of meningitis, sepsis, various tissue infections and community acquired pneumonia. In this paper antimicrobial susceptibilities of 289 H.influenzae strains isolated from various clinical samples between 2003-2006 were evaluated by disk diffusion method according to the recommendations of CLSI and beta-lactamase activity was investigated by nitrocefin hydrolysis test. Beta-lactamase activity was not detected in 2003 isolates. The percentage of beta-lactamase positive strains increased to 8 % and 7 % in 2005 and 2006, respectively. Similarly, resistance rates to trimethoprim-sulfamethoxazole increased from 29 % (2003) to 36 % (2006). When all isolates were evaluated, resistance rates for ampicillin and trimethoprimsulfamethoxazole were 5.9 % and 31.8 %. None of the isolates were resistant to cefotaxime, cefuroxime, amoxicillin-clavulanate. Similarly, beta-lactamase negative ampicillin resistant (BLNAR) isolates were not detected.